B12 Combi 10.000® met folaat by Vitakruid

Supports reduced fatigue and low energy

This high-quality combination helps reduce fatigue and low energy. It also supports nervous system function. It supports red blood cell formation. It supports the cell renewal process. The nutrients in this formula also support the immune system. They support mood. They support memory. They support concentration. This product is versatile and innovative.

First choice for very low vitamin B12 levels

B12 Combi 10.000® combines high-dose vitamin B12 with Quatrefolic®. This combination is the core of the formula. If you have very low vitamin B12 levels, we recommend B12 Combi 10.000® with folate. We added folate to support vitamin B12 absorption.

Quatrefolic® is an award-nominated folate form

Quatrefolic® received recognition in several industry awards. Examples include the Most Effective Strategic Product Development Award. It also reached finalist positions for Best New Ingredient. It also reached finalist positions for Finished Product of the Year in the Medical Food category. Quatrefolic® is a leading folate form worldwide.

High-dose vitamin B12 combination

B12 Combi 10.000® with folate contains two active forms of vitamin B12. It contains methylcobalamin (5000 mcg). It contains adenosylcobalamin (5000 mcg). Vitamin B12 is water-soluble. This is why vitamin B12 supplements can exceed the reference intake by a large margin. This is considered safe. Research has not linked high vitamin B12 intake to harmful effects.

Quatrefolic® (5-MTHF) supports absorption

Quatrefolic® is also called a fourth-generation folate form. It has higher bioavailability than synthetic folic acid forms. We support stability by binding it to a glucosamine salt instead of a calcium salt. Many standard folic acid forms must first convert into 5-MTHF before the body can use them. Quatrefolic® already contains the active form 5-MTHF. This means the body does not need extra support nutrients for conversion. Quatrefolic® is a leading folate form worldwide.

Folate supports better vitamin B12 function

Methylation is an important biochemical process in the body. This formula supports methylation with key cofactors. That is why we added Quatrefolic® to the two vitamin B12 forms. Folate supports methylation and supports vitamin B12 function. This is a highly absorbable form of vitamin B11. The body does not need to convert it. This helps the body use folate without extra conversion nutrients.

Best absorbed forms of vitamin B12

Methylcobalamin and adenosylcobalamin are well-absorbed forms of vitamin B12. They are biologically active forms. The body does not need to convert them in the stomach and intestines. Conversion steps can fail in some cases. Both methylcobalamin and adenosylcobalamin offer key biochemical benefits compared to inactive forms of vitamin B12. An example of an inactive synthetic form is cyanocobalamin. Manufacturers often use this form because it is stable and low-cost.

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Patented ingredients

Quatrefolic® is a patented product and a registered trademark of Gnosis.

Other information

Dietary supplement Vitamin supplement

Produced by Vitakruid BV
Jacobusspijkerdreef 430
2132 PZ Hoofddorp

For Smeets & Graas
G. Meirstraat 11
9728 TB Groningen
050 850 36 88

Last page change
6 februari 2026